This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PAX6-20-RE | 20 (40 μL) | 200 μL |  |
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| PAX6-20-OR | 20 (40 μL) | 200 μL |  |
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| PAX6-20-GO | 20 (40 μL) | 200 μL |  |
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| PAX6-20-GR | 20 (40 μL) | 200 μL |  |
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| PAX6-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015]
Gene Symbol : PAX6
Gene Name : Paired box 6
Chromosome : CHR 11: 318,179,60-317,847,91
Locus : 11p13
Alt. Genes : LRPPRC
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