This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PAX8-20-RE | 20 (40 μL) | 200 μL |  |
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| PAX8-20-OR | 20 (40 μL) | 200 μL |  |
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| PAX8-20-GO | 20 (40 μL) | 200 μL |  |
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| PAX8-20-GR | 20 (40 μL) | 200 μL |  |
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| PAX8-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]
Gene Symbol : PAX8
Gene Name : Paired box 8
Chromosome : CHR 2: 113,278,949-113,215,996
Locus : 2q14.1
Alt. Genes : ABI2
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