The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PCNT-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PCNT-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PCNT-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PCNT-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PCNT-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Gene Symbol : PCNT
Gene Name : Pericentrin
Chromosome : CHR 21: 463,241,02-464,457,68
Locus : 21q22.3
Alt. Genes : AASS
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.