The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PDE1B-20-RE | 20 (40 μL) | 200 μL |  |
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| PDE1B-20-OR | 20 (40 μL) | 200 μL |  |
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| PDE1B-20-GO | 20 (40 μL) | 200 μL |  |
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| PDE1B-20-GR | 20 (40 μL) | 200 μL |  |
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| PDE1B-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
Gene Symbol : PDE1B
Gene Name : Phosphodiesterase 1B
Chromosome : CHR 12: 545,493,92-545,792,38
Locus : 12q13.2
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