This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PDE3A-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PDE3A-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PDE3A-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PDE3A-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PDE3A-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Gene Symbol : PDE3A
Gene Name : Phosphodiesterase 3A
Chromosome : CHR 12: 203,692,44-206,841,06
Locus : 12p12.2
Alt. Genes : EBI3
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.