This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PDE4B-20-RE | 20 (40 μL) | 200 μL |  |
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| PDE4B-20-OR | 20 (40 μL) | 200 μL |  |
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| PDE4B-20-GO | 20 (40 μL) | 200 μL |  |
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| PDE4B-20-GR | 20 (40 μL) | 200 μL |  |
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| PDE4B-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Gene Symbol : PDE4B
Gene Name : Phosphodiesterase 4B
Chromosome : CHR 1: 657,925,09-663,745,78
Locus : 1p31.3
Alt. Genes : TRAP1
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