This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PDE5A-20-RE | 20 (40 μL) | 200 μL |  |
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| PDE5A-20-OR | 20 (40 μL) | 200 μL |  |
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| PDE5A-20-GO | 20 (40 μL) | 200 μL |  |
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| PDE5A-20-GR | 20 (40 μL) | 200 μL |  |
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| PDE5A-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Symbol : PDE5A
Gene Name : Phosphodiesterase 5A
Chromosome : CHR 4: 119,629,079-119,494,394
Locus : 4q26
Alt. Genes : ZNF263
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