This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PDGFA-20-RE | 20 (40 μL) | 200 μL |  |
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| PDGFA-20-OR | 20 (40 μL) | 200 μL |  |
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| PDGFA-20-GO | 20 (40 μL) | 200 μL |  |
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| PDGFA-20-GR | 20 (40 μL) | 200 μL |  |
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| PDGFA-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Gene Symbol : PDGFA
Gene Name : Platelet derived growth factor subunit A
Chromosome : CHR 7: 520,667-497,244
Locus : 7p22.3
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