This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PDGFRL-20-RE | 20 (40 μL) | 200 μL |  |
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| PDGFRL-20-OR | 20 (40 μL) | 200 μL |  |
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| PDGFRL-20-GO | 20 (40 μL) | 200 μL |  |
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| PDGFRL-20-GR | 20 (40 μL) | 200 μL |  |
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| PDGFRL-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor. [provided by RefSeq, Jul 2008]
Gene Symbol : PDGFRL
Gene Name : Platelet derived growth factor receptor like
Chromosome : CHR 8: 175,764,32-176,431,32
Locus : 8p22
Alt. Genes : ZNF263
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