This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has has an N-terminal ER-signal sequence, two thioredoxin (TRX) domains with non-classical Ser-Lys-Gln-Ser and Ser-Lys-Lys-Cys motifs, respectively, two TRX-like domains, and a C-terminal ER-retention sequence. The protein lacks oxidoreductase activity in vitro and probably functions as a chaperone. This gene's expression appears to be limited to the testis. [provided by RefSeq, Dec 2016]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
PDILT-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
PDILT-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
PDILT-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
PDILT-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
PDILT-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has has an N-terminal ER-signal sequence, two thioredoxin (TRX) domains with non-classical Ser-Lys-Gln-Ser and Ser-Lys-Lys-Cys motifs, respectively, two TRX-like domains, and a C-terminal ER-retention sequence. The protein lacks oxidoreductase activity in vitro and probably functions as a chaperone. This gene's expression appears to be limited to the testis. [provided by RefSeq, Dec 2016]
Gene Symbol : PDILT
Gene Name : Protein disulfide isomerase like, testis expressed
Chromosome : CHR 16: 204,047,41-203,591,69
Locus : 16p12.3
Alt. Genes : CEBPZ
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