Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PDK1-20-RE | 20 (40 μL) | 200 μL |  |
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| PDK1-20-OR | 20 (40 μL) | 200 μL |  |
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| PDK1-20-GO | 20 (40 μL) | 200 μL |  |
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| PDK1-20-GR | 20 (40 μL) | 200 μL |  |
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| PDK1-20-AQ | 20 (40 μL) | 200 μL |  |
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Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]
Gene Symbol : PDK1
Gene Name : Pyruvate dehydrogenase kinase 1
Chromosome : CHR 2: 172,555,372-172,672,692
Locus : 2q31.1
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