This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PDLIM2-20-RE | 20 (40 μL) | 200 μL |  |
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| PDLIM2-20-OR | 20 (40 μL) | 200 μL |  |
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| PDLIM2-20-GO | 20 (40 μL) | 200 μL |  |
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| PDLIM2-20-GR | 20 (40 μL) | 200 μL |  |
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| PDLIM2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
Gene Symbol : PDLIM2
Gene Name : PDZ and LIM domain 2
Chromosome : CHR 8: 225,787,40-225,980,24
Locus : 8p21.3
Alt. Genes : LINC01587
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