Pyruvate dehydrogenase complex (PDC) catalyzes the oxidative decarboxylation of pyruvate and links glycolysis to the tricarboxylic acid cycle and fatty acid synthesis. The dephosphorylation and reactivation of PDC is catalyzed by pyruvate dehydrogenase phosphatase (PDP). The dimeric PDP has a catalytic subunit and a regulatory subunit. This gene encodes the FAD-containing regulatory subunit of PDP. The encoded protein acts to decrease the sensitivity of the PDP catalytic subunit to magnesium ions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2017]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
PDPR-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
PDPR-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
PDPR-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
PDPR-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
PDPR-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
Pyruvate dehydrogenase complex (PDC) catalyzes the oxidative decarboxylation of pyruvate and links glycolysis to the tricarboxylic acid cycle and fatty acid synthesis. The dephosphorylation and reactivation of PDC is catalyzed by pyruvate dehydrogenase phosphatase (PDP). The dimeric PDP has a catalytic subunit and a regulatory subunit. This gene encodes the FAD-containing regulatory subunit of PDP. The encoded protein acts to decrease the sensitivity of the PDP catalytic subunit to magnesium ions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2017]
Gene Symbol : PDPR
Gene Name : Pyruvate dehydrogenase phosphatase regulatory subunit
Chromosome : CHR 16: 701,136,25-701,636,29
Locus : 16q22.1
Alt. Genes : YAF2
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