This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq, Jul 2008]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
PEX14-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
PEX14-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
PEX14-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
PEX14-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
PEX14-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq, Jul 2008]
Gene Symbol : PEX14
Gene Name : Peroxisomal biogenesis factor 14
Chromosome : CHR 1: 104,749,45-106,307,57
Locus : 1p36.22
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