Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PGGT1B-20-RE | 20 (40 μL) | 200 μL |  |
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| PGGT1B-20-OR | 20 (40 μL) | 200 μL |  |
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| PGGT1B-20-GO | 20 (40 μL) | 200 μL |  |
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| PGGT1B-20-GR | 20 (40 μL) | 200 μL |  |
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| PGGT1B-20-AQ | 20 (40 μL) | 200 μL |  |
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Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010]
Gene Symbol : PGGT1B
Gene Name : Protein geranylgeranyltransferase type I subunit beta
Chromosome : CHR 5: 115,262,886-115,200,246
Locus : 5q22.3
Alt. Genes : FEM1B
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