This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PHLPP1-20-RE | 20 (40 μL) | 200 μL |  |
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| PHLPP1-20-OR | 20 (40 μL) | 200 μL |  |
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| PHLPP1-20-GO | 20 (40 μL) | 200 μL |  |
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| PHLPP1-20-GR | 20 (40 μL) | 200 μL |  |
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| PHLPP1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011]
Gene Symbol : PHLPP1
Gene Name : PH domain and leucine rich repeat protein phosphatase 1
Chromosome : CHR 18: 627,154,38-629,804,42
Locus : 18q21.33
Alt. Genes : OPTN
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