PIAS2 FISH Probe

This gene encodes a member of the protein inhibitor of activated STAT family, which function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2017]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
PIAS2-20-RE 20 (40 μL) 200 μL color Request Pricing
PIAS2-20-OR 20 (40 μL) 200 μL color Request Pricing
PIAS2-20-GO 20 (40 μL) 200 μL color Request Pricing
PIAS2-20-GR 20 (40 μL) 200 μL color Request Pricing
PIAS2-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes a member of the protein inhibitor of activated STAT family, which function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2017]

Gene Details

Gene Symbol : PIAS2

Gene Name : Protein inhibitor of activated STAT 2

Chromosome : CHR 18: 469,201,66-468,032,23

Locus : 18q21.1

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