PIGP FISH Probe

This gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). This gene is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. This gene has multiple pseudogenes and is a member of the phosphatidylinositol glycan anchor biosynthesis gene family. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Feb 2016]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
PIGP-20-RE 20 (40 μL) 200 μL color Request Pricing
PIGP-20-OR 20 (40 μL) 200 μL color Request Pricing
PIGP-20-GO 20 (40 μL) 200 μL color Request Pricing
PIGP-20-GR 20 (40 μL) 200 μL color Request Pricing
PIGP-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). This gene is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. This gene has multiple pseudogenes and is a member of the phosphatidylinositol glycan anchor biosynthesis gene family. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Feb 2016]

Gene Details

Gene Symbol : PIGP

Gene Name : Phosphatidylinositol glycan anchor biosynthesis class P

Chromosome : CHR 21: 370,731,57-370,653,63

Locus : 21q22.13

Alt. Genes : PREB

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