The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PIK3C2G-20-RE | 20 (40 μL) | 200 μL |  |
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| PIK3C2G-20-OR | 20 (40 μL) | 200 μL |  |
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| PIK3C2G-20-GO | 20 (40 μL) | 200 μL |  |
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| PIK3C2G-20-GR | 20 (40 μL) | 200 μL |  |
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| PIK3C2G-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Symbol : PIK3C2G
Gene Name : Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
Chromosome : CHR 12: 182,429,45-187,168,60
Locus : 12p12.3
Alt. Genes : EBI3
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