This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PIK3CB-20-RE | 20 (40 μL) | 200 μL |  |
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| PIK3CB-20-OR | 20 (40 μL) | 200 μL |  |
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| PIK3CB-20-GO | 20 (40 μL) | 200 μL |  |
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| PIK3CB-20-GR | 20 (40 μL) | 200 μL |  |
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| PIK3CB-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
Gene Symbol : PIK3CB
Gene Name : Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
Chromosome : CHR 3: 138,834,937-138,652,697
Locus : 3q22.3
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