Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PIK3R1-20-RE | 20 (40 μL) | 200 μL |  |
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| PIK3R1-20-OR | 20 (40 μL) | 200 μL |  |
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| PIK3R1-20-GO | 20 (40 μL) | 200 μL |  |
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| PIK3R1-20-GR | 20 (40 μL) | 200 μL |  |
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| PIK3R1-20-AQ | 20 (40 μL) | 200 μL |  |
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Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
Gene Symbol : PIK3R1
Gene Name : Phosphoinositide-3-kinase regulatory subunit 1
Chromosome : CHR 5: 682,157,36-683,018,20
Locus : 5q13.1
Alt. Genes : LRPPRC
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