Phosphoinositide 3-kinase gamma is a lipid kinase that produces the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate. The kinase is composed of a catalytic subunit and one of several regulatory subunits, and is chiefly activated by G protein-coupled receptors. This gene encodes a regulatory subunit, and is distantly related to the phosphoinositide-3-kinase, regulatory subunit 5 gene which is located adjacent to this gene on chromosome 7. The orthologous protein in the mouse binds to both the catalytic subunit and to G(beta/gamma), and mediates activation of the kinase subunit downstream of G protein-coupled receptors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PIK3R6-20-RE | 20 (40 μL) | 200 μL |  |
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| PIK3R6-20-OR | 20 (40 μL) | 200 μL |  |
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| PIK3R6-20-GO | 20 (40 μL) | 200 μL |  |
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| PIK3R6-20-GR | 20 (40 μL) | 200 μL |  |
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| PIK3R6-20-AQ | 20 (40 μL) | 200 μL |  |
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Phosphoinositide 3-kinase gamma is a lipid kinase that produces the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate. The kinase is composed of a catalytic subunit and one of several regulatory subunits, and is chiefly activated by G protein-coupled receptors. This gene encodes a regulatory subunit, and is distantly related to the phosphoinositide-3-kinase, regulatory subunit 5 gene which is located adjacent to this gene on chromosome 7. The orthologous protein in the mouse binds to both the catalytic subunit and to G(beta/gamma), and mediates activation of the kinase subunit downstream of G protein-coupled receptors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Gene Symbol : PIK3R6
Gene Name : Phosphoinositide-3-kinase regulatory subunit 6
Chromosome : CHR 17: 887,000,2-880,272,2
Locus : 17p13.1
Alt. Genes : CEBPZ
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