This gene encodes a member of the phospholipase A2 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This calcium-dependent enzyme hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids. In one example, this enzyme catalyzes the release of arachidonic acid from cell membrane phospholipids, thus playing a role in the production of various inflammatory lipid mediators, such as prostaglandins. The encoded protein may promote the survival of breast cancer cells through its role in lipid metabolism. [provided by RefSeq, Nov 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PLA2G10-20-RE | 20 (40 μL) | 200 μL |  |
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| PLA2G10-20-OR | 20 (40 μL) | 200 μL |  |
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| PLA2G10-20-GO | 20 (40 μL) | 200 μL |  |
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| PLA2G10-20-GR | 20 (40 μL) | 200 μL |  |
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| PLA2G10-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the phospholipase A2 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This calcium-dependent enzyme hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids. In one example, this enzyme catalyzes the release of arachidonic acid from cell membrane phospholipids, thus playing a role in the production of various inflammatory lipid mediators, such as prostaglandins. The encoded protein may promote the survival of breast cancer cells through its role in lipid metabolism. [provided by RefSeq, Nov 2015]
Gene Symbol : PLA2G10
Gene Name : Phospholipase A2 group X
Chromosome : CHR 16: 146,946,62-146,725,47
Locus : 16p13.12
Alt. Genes : ZNF197
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