Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PLAG1-20-RE | 20 (40 μL) | 200 μL |  |
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| PLAG1-20-OR | 20 (40 μL) | 200 μL |  |
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| PLAG1-20-GO | 20 (40 μL) | 200 μL |  |
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| PLAG1-20-GR | 20 (40 μL) | 200 μL |  |
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| PLAG1-20-AQ | 20 (40 μL) | 200 μL |  |
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Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Symbol : PLAG1
Gene Name : PLAG1 zinc finger
Chromosome : CHR 8: 562,113,26-561,609,08
Locus : 8q12.1
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