This gene encodes a membrane-associated phospholipase that displays lysophospholipase and phospholipase A2 activities through removal of sn-1 and sn-2 fatty acids of glycerophospholipids. In addition, it displays lipase and retinyl ester hydrolase activities. The encoded protein is highly conserved and is composed of a large, glycosylated extracellular domain composed of four tandem homologous domains, followed by a hydrophobic segment that anchors the enzyme to the membrane and a short C-terminal cytoplasmic tail. This gene has been identified as a candidate rheumatoid arthritis risk gene. [provided by RefSeq, Jul 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PLB1-20-RE | 20 (40 μL) | 200 μL |  |
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| PLB1-20-OR | 20 (40 μL) | 200 μL |  |
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| PLB1-20-GO | 20 (40 μL) | 200 μL |  |
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| PLB1-20-GR | 20 (40 μL) | 200 μL |  |
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| PLB1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a membrane-associated phospholipase that displays lysophospholipase and phospholipase A2 activities through removal of sn-1 and sn-2 fatty acids of glycerophospholipids. In addition, it displays lipase and retinyl ester hydrolase activities. The encoded protein is highly conserved and is composed of a large, glycosylated extracellular domain composed of four tandem homologous domains, followed by a hydrophobic segment that anchors the enzyme to the membrane and a short C-terminal cytoplasmic tail. This gene has been identified as a candidate rheumatoid arthritis risk gene. [provided by RefSeq, Jul 2016]
Gene Symbol : PLB1
Gene Name : Phospholipase B1
Chromosome : CHR 2: 284,885,78-286,441,34
Locus : 2p23.2
Alt. Genes : RBM12
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