This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PLCD1-20-RE | 20 (40 μL) | 200 μL |  |
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| PLCD1-20-OR | 20 (40 μL) | 200 μL |  |
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| PLCD1-20-GO | 20 (40 μL) | 200 μL |  |
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| PLCD1-20-GR | 20 (40 μL) | 200 μL |  |
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| PLCD1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Symbol : PLCD1
Gene Name : Phospholipase C delta 1
Chromosome : CHR 3: 380,296,62-380,074,95
Locus : 3p22.2
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