The protein encoded by this gene is a member of the phosphoinositide-specific phospholipase C family. Members in this family, classified into six isotypes that are tissue- and organ-specific, hydrolyze phosphatidylinositol 4,5-bisphosphate just before the phosphate group to yield diacylglycerol and inositol 1,4,5-trisphosphate. This protein localizes to the acrosome in spermatozoa and elicits Ca(2+) oscillations and egg activation during fertilization that leads to early embryonic development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PLCZ1-20-RE | 20 (40 μL) | 200 μL |  |
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| PLCZ1-20-OR | 20 (40 μL) | 200 μL |  |
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| PLCZ1-20-GO | 20 (40 μL) | 200 μL |  |
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| PLCZ1-20-GR | 20 (40 μL) | 200 μL |  |
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| PLCZ1-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a member of the phosphoinositide-specific phospholipase C family. Members in this family, classified into six isotypes that are tissue- and organ-specific, hydrolyze phosphatidylinositol 4,5-bisphosphate just before the phosphate group to yield diacylglycerol and inositol 1,4,5-trisphosphate. This protein localizes to the acrosome in spermatozoa and elicits Ca(2+) oscillations and egg activation during fertilization that leads to early embryonic development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Gene Symbol : PLCZ1
Gene Name : Phospholipase C zeta 1
Chromosome : CHR 12: 187,380,58-186,455,28
Locus : 12p12.3
Alt. Genes : RASA4
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