The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
PLG-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
PLG-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
PLG-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
PLG-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
PLG-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]
Gene Symbol : PLG
Gene Name : Plasminogen
Chromosome : CHR 6: 160,702,192-160,754,053
Locus : 6q26
Alt. Genes : CLEC3A
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