This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PLXNA2-20-RE | 20 (40 μL) | 200 μL |  |
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| PLXNA2-20-OR | 20 (40 μL) | 200 μL |  |
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| PLXNA2-20-GO | 20 (40 μL) | 200 μL |  |
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| PLXNA2-20-GR | 20 (40 μL) | 200 μL |  |
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| PLXNA2-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C. [provided by RefSeq, Jul 2008]
Gene Symbol : PLXNA2
Gene Name : Plexin A2
Chromosome : CHR 1: 208,244,383-208,022,241
Locus : 1q32.2
Alt. Genes : OPTN
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