This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PMS1-20-RE | 20 (40 μL) | 200 μL |  |
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| PMS1-20-OR | 20 (40 μL) | 200 μL |  |
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| PMS1-20-GO | 20 (40 μL) | 200 μL |  |
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| PMS1-20-GR | 20 (40 μL) | 200 μL |  |
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| PMS1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008]
Gene Symbol : PMS1
Gene Name : PMS1 homolog 1, mismatch repair system component
Chromosome : CHR 2: 189,784,084-189,877,628
Locus : 2q32.2
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