This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PNPLA6-20-RE | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PNPLA6-20-OR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PNPLA6-20-GO | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PNPLA6-20-GR | 20 (40 μL) | 200 μL |  |
Request Pricing |
| PNPLA6-20-AQ | 20 (40 μL) | 200 μL |  |
Request Pricing |
This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Symbol : PNPLA6
Gene Name : Patatin like phospholipase domain containing 6
Chromosome : CHR 19: 753,415,1-756,176,6
Locus : 19p13.2
Alt. Genes : OPTN
Lorem Ipsum is simply dummy text of the printing and typesetting industry.
Lorem Ipsum is simply dummy text of the printing and typesetting industry.