Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).[supplied by OMIM, Mar 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| POFUT2-20-RE | 20 (40 μL) | 200 μL |  |
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| POFUT2-20-OR | 20 (40 μL) | 200 μL |  |
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| POFUT2-20-GO | 20 (40 μL) | 200 μL |  |
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| POFUT2-20-GR | 20 (40 μL) | 200 μL |  |
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| POFUT2-20-AQ | 20 (40 μL) | 200 μL |  |
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Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).[supplied by OMIM, Mar 2008]
Gene Symbol : POFUT2
Gene Name : Protein O-fucosyltransferase 2
Chromosome : CHR 21: 452,879,11-452,639,27
Locus : 21q22.3
Alt. Genes : LRPPRC
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