The protein encoded by this gene is an error-prone DNA polymerase involved in DNA repair. The encoded protein promotes DNA synthesis across lesions in the template DNA, which other polymerases cannot do. The encoded polymerase inserts deoxynucleotides across lesions and then relies on DNA polymerase zeta to extend the nascent DNA strand to bypass the lesion. [provided by RefSeq, May 2017]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| POLI-20-RE | 20 (40 μL) | 200 μL |  |
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| POLI-20-OR | 20 (40 μL) | 200 μL |  |
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| POLI-20-GO | 20 (40 μL) | 200 μL |  |
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| POLI-20-GR | 20 (40 μL) | 200 μL |  |
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| POLI-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is an error-prone DNA polymerase involved in DNA repair. The encoded protein promotes DNA synthesis across lesions in the template DNA, which other polymerases cannot do. The encoded polymerase inserts deoxynucleotides across lesions and then relies on DNA polymerase zeta to extend the nascent DNA strand to bypass the lesion. [provided by RefSeq, May 2017]
Gene Symbol : POLI
Gene Name : DNA polymerase iota
Chromosome : CHR 18: 542,694,78-543,212,65
Locus : 18q21.2
Alt. Genes : FEM1B
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