This gene encodes the second largest subunit of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into precursors of mRNA, snRNA and microRNA. This subunit and the largest subunit form opposite sides of the center cleft of Pol II. Deletion of the flap loop region of this subunit results in a decrease in the rate of transcriptional elongation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| POLR2B-20-RE | 20 (40 μL) | 200 μL |  |
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| POLR2B-20-OR | 20 (40 μL) | 200 μL |  |
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| POLR2B-20-GO | 20 (40 μL) | 200 μL |  |
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| POLR2B-20-GR | 20 (40 μL) | 200 μL |  |
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| POLR2B-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the second largest subunit of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into precursors of mRNA, snRNA and microRNA. This subunit and the largest subunit form opposite sides of the center cleft of Pol II. Deletion of the flap loop region of this subunit results in a decrease in the rate of transcriptional elongation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Symbol : POLR2B
Gene Name : RNA polymerase II subunit B
Chromosome : CHR 4: 569,786,39-570,311,61
Locus : 4q12
Alt. Genes : HIPK3
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