This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| POLR2E-20-RE | 20 (40 μL) | 200 μL |  |
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| POLR2E-20-OR | 20 (40 μL) | 200 μL |  |
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| POLR2E-20-GO | 20 (40 μL) | 200 μL |  |
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| POLR2E-20-GR | 20 (40 μL) | 200 μL |  |
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| POLR2E-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Gene Symbol : POLR2E
Gene Name : RNA polymerase II subunit E
Chromosome : CHR 19: 109,539,1-108,657,8
Locus : 19p13.3
Alt. Genes : ZNF263
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