PON1 FISH Probe

This gene encodes a member of the paraoxonase family of enzymes and exhibits lactonase and ester hydrolase activity. Following synthesis in the kidney and liver, the enzyme is secreted into the circulation, where it binds to high density lipoprotein (HDL) particles and hydrolyzes thiolactones and xenobiotics, including paraoxon, a metabolite of the insecticide parathion. Polymorphisms in this gene may be associated with coronary artery disease and diabetic retinopathy. The gene is found in a cluster of three related paraoxonase genes on chromosome 7. [provided by RefSeq, Aug 2017]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
PON1-20-RE 20 (40 μL) 200 μL color Request Pricing
PON1-20-OR 20 (40 μL) 200 μL color Request Pricing
PON1-20-GO 20 (40 μL) 200 μL color Request Pricing
PON1-20-GR 20 (40 μL) 200 μL color Request Pricing
PON1-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes a member of the paraoxonase family of enzymes and exhibits lactonase and ester hydrolase activity. Following synthesis in the kidney and liver, the enzyme is secreted into the circulation, where it binds to high density lipoprotein (HDL) particles and hydrolyzes thiolactones and xenobiotics, including paraoxon, a metabolite of the insecticide parathion. Polymorphisms in this gene may be associated with coronary artery disease and diabetic retinopathy. The gene is found in a cluster of three related paraoxonase genes on chromosome 7. [provided by RefSeq, Aug 2017]

Gene Details

Gene Symbol : PON1

Gene Name : Paraoxonase 1

Chromosome : CHR 7: 953,245,71-952,983,56

Locus : 7q21.3

Alt. Genes : ZNF197

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