This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described; however, only one has been fully characterized. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PON3-20-RE | 20 (40 μL) | 200 μL |  |
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| PON3-20-OR | 20 (40 μL) | 200 μL |  |
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| PON3-20-GO | 20 (40 μL) | 200 μL |  |
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| PON3-20-GR | 20 (40 μL) | 200 μL |  |
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| PON3-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene is a member of the paraoxonase family and lies in a cluster on chromosome 7 with the other two family members. The encoded protein is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis. Alternatively spliced variants which encode different protein isoforms have been described; however, only one has been fully characterized. [provided by RefSeq, Jul 2008]
Gene Symbol : PON3
Gene Name : Paraoxonase 3
Chromosome : CHR 7: 953,963,74-953,598,71
Locus : 7q21.3
Alt. Genes : FARP1
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