This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
POU6F2-20-RE | 20 (40 μL) | 200 μL | Request Pricing | |
POU6F2-20-OR | 20 (40 μL) | 200 μL | Request Pricing | |
POU6F2-20-GO | 20 (40 μL) | 200 μL | Request Pricing | |
POU6F2-20-GR | 20 (40 μL) | 200 μL | Request Pricing | |
POU6F2-20-AQ | 20 (40 μL) | 200 μL | Request Pricing |
This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
Gene Symbol : POU6F2
Gene Name : POU class 6 homeobox 2
Chromosome : CHR 7: 389,778,77-394,686,00
Locus : 7p14.1
Alt. Genes : FEM1B
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