This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PPARG-20-RE | 20 (40 μL) | 200 μL |  |
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| PPARG-20-OR | 20 (40 μL) | 200 μL |  |
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| PPARG-20-GO | 20 (40 μL) | 200 μL |  |
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| PPARG-20-GR | 20 (40 μL) | 200 μL |  |
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| PPARG-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Symbol : PPARG
Gene Name : Peroxisome proliferator activated receptor gamma
Chromosome : CHR 3: 122,878,49-124,710,53
Locus : 3p25.2
Alt. Genes : TSFM
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