The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. [provided by RefSeq, Nov 2014]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PPBP-20-RE | 20 (40 μL) | 200 μL |  |
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| PPBP-20-OR | 20 (40 μL) | 200 μL |  |
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| PPBP-20-GO | 20 (40 μL) | 200 μL |  |
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| PPBP-20-GR | 20 (40 μL) | 200 μL |  |
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| PPBP-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. [provided by RefSeq, Nov 2014]
Gene Symbol : PPBP
Gene Name : Pro-platelet basic protein
Chromosome : CHR 4: 739,881,89-739,864,38
Locus : 4q13.3
Alt. Genes : BET1
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