This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PPP1R8-20-RE | 20 (40 μL) | 200 μL |  |
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| PPP1R8-20-OR | 20 (40 μL) | 200 μL |  |
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| PPP1R8-20-GO | 20 (40 μL) | 200 μL |  |
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| PPP1R8-20-GR | 20 (40 μL) | 200 μL |  |
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| PPP1R8-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008]
Gene Symbol : PPP1R8
Gene Name : Protein phosphatase 1 regulatory subunit 8
Chromosome : CHR 1: 278,307,40-278,516,71
Locus : 1p35.3
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