This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PPP2R1B-20-RE | 20 (40 μL) | 200 μL |  |
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| PPP2R1B-20-OR | 20 (40 μL) | 200 μL |  |
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| PPP2R1B-20-GO | 20 (40 μL) | 200 μL |  |
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| PPP2R1B-20-GR | 20 (40 μL) | 200 μL |  |
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| PPP2R1B-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. [provided by RefSeq, Apr 2010]
Gene Symbol : PPP2R1B
Gene Name : Protein phosphatase 2 scaffold subunit Abeta
Chromosome : CHR 11: 111,766,444-111,694,568
Locus : 11q23.1
Alt. Genes : TRIM28
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