This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRCC-20-RE | 20 (40 μL) | 200 μL |  |
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| PRCC-20-OR | 20 (40 μL) | 200 μL |  |
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| PRCC-20-GO | 20 (40 μL) | 200 μL |  |
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| PRCC-20-GR | 20 (40 μL) | 200 μL |  |
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| PRCC-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010]
Gene Symbol : PRCC
Gene Name : Papillary renal cell carcinoma (translocation-associated)
Chromosome : CHR 1: 156,767,481-156,800,818
Locus : 1q23.1
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