This gene encodes a DNA primase-polymerase that belongs to a superfamily of archaeao-eukaryotic primases. Members of this family have primase activity, catalyzing the synthesis of short RNA primers that serve as starting points for DNA synthesis, as well as DNA polymerase activity. The encoded protein facilitates DNA damage tolerance by mediating uninterrupted fork progression after UV irradiation and reinitiating DNA synthesis. An allelic variant in this gene is associated with myopia 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRIMPOL-20-RE | 20 (40 μL) | 200 μL |  |
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| PRIMPOL-20-OR | 20 (40 μL) | 200 μL |  |
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| PRIMPOL-20-GO | 20 (40 μL) | 200 μL |  |
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| PRIMPOL-20-GR | 20 (40 μL) | 200 μL |  |
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| PRIMPOL-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a DNA primase-polymerase that belongs to a superfamily of archaeao-eukaryotic primases. Members of this family have primase activity, catalyzing the synthesis of short RNA primers that serve as starting points for DNA synthesis, as well as DNA polymerase activity. The encoded protein facilitates DNA damage tolerance by mediating uninterrupted fork progression after UV irradiation and reinitiating DNA synthesis. An allelic variant in this gene is associated with myopia 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Gene Symbol : PRIMPOL
Gene Name : Primase and DNA directed polymerase
Chromosome : CHR 4: 184,649,612-184,694,958
Locus : 4q35.1
Alt. Genes : ENAM
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