This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRLR-20-RE | 20 (40 μL) | 200 μL |  |
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| PRLR-20-OR | 20 (40 μL) | 200 μL |  |
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| PRLR-20-GO | 20 (40 μL) | 200 μL |  |
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| PRLR-20-GR | 20 (40 μL) | 200 μL |  |
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| PRLR-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]
Gene Symbol : PRLR
Gene Name : Prolactin receptor
Chromosome : CHR 5: 352,305,88-350,482,94
Locus : 5p13.2
Alt. Genes : HIPK3
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