This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRMT1-20-RE | 20 (40 μL) | 200 μL |  |
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| PRMT1-20-OR | 20 (40 μL) | 200 μL |  |
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| PRMT1-20-GO | 20 (40 μL) | 200 μL |  |
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| PRMT1-20-GR | 20 (40 μL) | 200 μL |  |
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| PRMT1-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]
Gene Symbol : PRMT1
Gene Name : Protein arginine methyltransferase 1
Chromosome : CHR 19: 496,761,65-496,884,49
Locus : 19q13.33
Alt. Genes : ZNF263
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