This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PROC-20-RE | 20 (40 μL) | 200 μL |  |
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| PROC-20-OR | 20 (40 μL) | 200 μL |  |
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| PROC-20-GO | 20 (40 μL) | 200 μL |  |
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| PROC-20-GR | 20 (40 μL) | 200 μL |  |
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| PROC-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009]
Gene Symbol : PROC
Gene Name : Protein C, inactivator of coagulation factors Va and VIIIa
Chromosome : CHR 2: 127,418,220-127,429,245
Locus : 2q14.3
Alt. Genes : CELA3A
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