PROS1 FISH Probe

This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Oct 2015]


Gene Details
SKU Test Kits Buffer Dye Color Order Now
PROS1-20-RE 20 (40 μL) 200 μL color Request Pricing
PROS1-20-OR 20 (40 μL) 200 μL color Request Pricing
PROS1-20-GO 20 (40 μL) 200 μL color Request Pricing
PROS1-20-GR 20 (40 μL) 200 μL color Request Pricing
PROS1-20-AQ 20 (40 μL) 200 μL color Request Pricing

Gene Summary

This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Oct 2015]

Gene Details

Gene Symbol : PROS1

Gene Name : Protein S

Chromosome : CHR 3: 939,740,89-938,730,36

Locus : 3q11.1

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