This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PROZ-20-RE | 20 (40 μL) | 200 μL |  |
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| PROZ-20-OR | 20 (40 μL) | 200 μL |  |
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| PROZ-20-GO | 20 (40 μL) | 200 μL |  |
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| PROZ-20-GR | 20 (40 μL) | 200 μL |  |
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| PROZ-20-AQ | 20 (40 μL) | 200 μL |  |
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This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Gene Symbol : PROZ
Gene Name : Protein Z, vitamin K dependent plasma glycoprotein
Chromosome : CHR 13: 113,155,863-113,172,385
Locus : 13q34
Alt. Genes : RBM7
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