The protein encoded by this gene is a single-pass transmembrane protein containing an N-terminal gamma-carboxyglutamic acid (Gla) domain and tandem Pro/Leu-Pro-Xaa-Tyr (PY) motifs at its C-terminal end. The Gla domain is exposed on the cell surface while the PY motifs are cytoplasmic. The PY motifs of the encoded protein have been shown to interact with YAP1, a WW domain-containing protein. Therefore, it is thought that the encoded protein may be part of a signal transduction pathway. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PRRG2-20-RE | 20 (40 μL) | 200 μL |  |
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| PRRG2-20-OR | 20 (40 μL) | 200 μL |  |
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| PRRG2-20-GO | 20 (40 μL) | 200 μL |  |
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| PRRG2-20-GR | 20 (40 μL) | 200 μL |  |
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| PRRG2-20-AQ | 20 (40 μL) | 200 μL |  |
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The protein encoded by this gene is a single-pass transmembrane protein containing an N-terminal gamma-carboxyglutamic acid (Gla) domain and tandem Pro/Leu-Pro-Xaa-Tyr (PY) motifs at its C-terminal end. The Gla domain is exposed on the cell surface while the PY motifs are cytoplasmic. The PY motifs of the encoded protein have been shown to interact with YAP1, a WW domain-containing protein. Therefore, it is thought that the encoded protein may be part of a signal transduction pathway. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Gene Symbol : PRRG2
Gene Name : Proline rich and Gla domain 2
Chromosome : CHR 19: 495,806,16-495,910,07
Locus : 19q13.33
Alt. Genes : YAF2
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